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Scientific and Clinical Evidence:

Microfragmented Adipose Tissue (MAT)

Microfragmented Adipose Tissue is supported by 100+ peer-reviewed publications with up to 3 years follow up (95% are independent studies from well-respected institutions).

  • Over 50,000 procedures have been performed in 8 years
  • Longest published follow-up is 3 years
  • 35 prospective studies with majority 1-2 years follow-up
  • 28 basic science articles evaluating the quality and characteristics of Microfragmented Adipose Tissue (MAT)
  • 95% independently conducted, investigator-initiated studies from distinguished institutions
  • Evidence includes an independent multicenter, international prospective study for elderly patients suffering from orthopaedic issues
  • 38 ongoing independent clinical studies at esteemed institutions
  • 11 Randomized Controlled Trials
  • 23 Prospective Studies
  • 4 Retrospective Studies
  • Military: Independent, multicenter randomized controlled trial for active military patients suffering from orthopaedic issues 

Benefits of Microfragmented Adipose Tissue (MAT) 

  • Microfragmented Adipose Tissue (MAT) remains structurally intact with preserved cell and tissue microarchitecture
    • Maintains vascular stroma: mainly characterized by slit-like capillaries with evident lumen and vascular channels, compared to compressed and distorted microchannels in the conventionally treated adipose tissue
    • Perivascular components: perivascular cells line capillaries and demonstrate increased concentration and enhanced viability compared to lipoaspirate
    • Tissue elements: composed of adipocytes, endothelial cells, mesenchymal cells and pericytes, structured in 200-500µm spherical clusters